abstract：:The major source of aluminum in patients with chronic renal failure treated by hemodialysis is the hemodialysis fluid. The aluminum is derived from both the water and the chemical concentrate used in the preparation of the hemodialysis fluid. Due to the complex physico-chemistry of aluminum in water and dialysis fluid...

journal_title：Clinical nephrology

authors： Rahman H,Channon SM,Parkinson IS,Skillen AW,Ward MK,Kerr DN

更新日期：1985-01-01 00:00:00

abstract：:We studied retrospectively the clinical course of 32 steroid sensitive nephrotic children with frequent relapses with or without steroid dependency associated with minimal glomerular lesions. Six hundred twenty-seven relapses were traced during a mean observation period of 7 years per patient. The median period betwee...

journal_title：Clinical nephrology

authors： Wingen AM,Müller-Wiefel DE,Schärer K

更新日期：1985-01-01 00:00:00

abstract：:We have studied vessel wall function in two groups of patients with chronic renal failure - 1) conservative treatment only and 2) maintenance hemodialysis. Three proteins synthesized by vascular endothelium-plasminogen activator (PA), factor VIII related antigen (VIII:RAg) and antithrombin III (ATIII) - were assayed b...

journal_title：Clinical nephrology

authors： Winter M,Needham J,Mackie I,Cameron JS

更新日期：1984-12-01 00:00:00

abstract：:Sera from 84 uremic patients (53 on conservative treatment and 31 on hemodialysis) were studied spectrofluorometrically in comparison with 20 normal subjects and 11 jaundiced patients. Serum fluorescence in patients with chronic renal failure was significantly higher than in normals and patients with jaundice. Two typ...

journal_title：Clinical nephrology

authors： Hadjivassiliou AG,Digenis GE,Mayopoulou-Symvoulidis D,Voudiclari S,Tsaparas N,Symvoulidis A

更新日期：1984-07-01 00:00:00

abstract：:Chronic hemodialysis (HD) and peritoneal dialysis (PD) patients in one dialysis center were examined for (EO)-related sensitization. Five of 56 (8.9%) HD patients and 0 of 30 PD patients skin tested with a conjugate of human serum albumin (HSA) and EO had positive skin prick tests. The sera of 13 of 107 (12.1%) HD pat...

journal_title：Clinical nephrology

authors： Marshall C,Shimizu A,Smith EK,Dolovich J

更新日期：1984-06-01 00:00:00

abstract：:Eleven cases of renal light chain deposition without amyloïdosis are reported (7 multiple myeloma, one Waldenström's disease, 3 without multiple myeloma without spike in serum or urine). Ten had kappa light chain deposits and 1 lambda light chain deposits along tubular basement membranes and in glomeruli. Ultrastructu...

journal_title：Clinical nephrology

authors： Noel LH,Droz D,Ganeval D,Grunfeld JP

更新日期：1984-05-01 00:00:00

abstract：:Antibody titers against 4 viruses of the herpes group have been studied in the sera of 54 patients with IgA glomerulonephritis (GN). The incidence of antibodies to herpes simplex virus type-1 (HSV-1), HSV-2, cytomegalovirus (CMV), Epstein-Barr virus nuclear antigen (EBNA), and that of IgG antibodies to EBV virus capsi...

journal_title：Clinical nephrology

authors： Nagy J,Uj M,Szücs G,Trinn C,Burger T

更新日期：1984-05-01 00:00:00

abstract：:A randomized double blind trial was performed to investigate the effect of the platelet aggregation inhibitor ticlopidine on the rate of decline in renal function in diabetic nephropathy. Twenty-two patients with insulin dependent diabetes complicated by nephropathy completed the trial--11 on ticlopidine, and 11 on pl...

journal_title：Clinical nephrology

authors： Nyberg G,Larsson O,Westberg NG,Aurell M,Jagenburg R,Blohmé G

更新日期：1984-03-01 00:00:00

abstract：:In 29 patients with high risk of bleeding, 111 hemodialyses have been performed without heparin (WHD) or other anticoagulants. The same patients were switched to low dose heparin dialysis (LDHD) as soon as the bleeding risk had ceased. The dialyzer had to be changed in 11 and the drip chamber in 20 WHDs because of par...

journal_title：Clinical nephrology

authors： Casati S,Moia M,Graziani G,Cantaluppi A,Citterio A,Mannucci PM,Ponticelli C

更新日期：1984-02-01 00:00:00

abstract：:Classification of proteinurias, based on physiopathology, was first comprehensively achieved about 1966 [Hardwicke 1970]. This classification, sometimes with minor modifications, has now received widespread acceptance, and the current status of proteinuria has been recently reviewed [Pesce and Furst 1979]. In this sho...

journal_title：Clinical nephrology

authors： Hardwicke J

更新日期：1984-01-01 00:00:00

abstract：:This study was undertaken to establish whether the Fc-receptor function of circulating monocytes (CM) and/or of splenic macrophages (SM) is modified during the course of minimal change nephrotic syndrome (MCNS) of childhood. The Fc-receptor function of SM was ascertained by measuring the spleen to liver uptake ratio 4...

journal_title：Clinical nephrology

authors： Davin JC,Foidart JB,Mahieu PR

更新日期：1983-12-01 00:00:00

abstract：:The polymerization of tubulin leads to the formation of microtubules which are one of the components of the axons of nerve cells. This reaction is the limiting factor in the growth of axons. Uremic middle molecules inhibit in vitro the polymerization of tubulin in a dose dependent way. It is possible that a similar ph...

journal_title：Clinical nephrology

authors： Braguer D,Chauvet-Monges AM,Sari JC,Crevat A,Durand C,Murisasco A,Elsen R

更新日期：1983-09-01 00:00:00

abstract：:We evaluated 30 first degree relatives of 9 patients with end-stage renal disease secondary to adult polycystic kidney disease. The diagnostic accuracy of renal ultrasonography was compared with intravenous pyelogram with nephrotomography. In 27 patients the two tests were in agreement. In 3 patients both tests were a...

journal_title：Clinical nephrology

authors： Sahney S,Sandler MA,Weiss L,Levin NW,Hricak H,Madrazo BL

更新日期：1983-08-01 00:00:00

abstract：:We present 5 patients with abnormal urinalysis from a series of 11 infants with congenital syphilis. Three of these 5 patients had a biopsy that demonstrated a membranous glomerulonephritis, and in two cases treponemal antigens were identified in the capillaries of the glomeruli. We suggest that glomerulonephritis wit...

journal_title：Clinical nephrology

authors： Sanchez-Bayle M,Ecija JL,Estepa R,Cambronero MJ,Martinez MA

更新日期：1983-07-01 00:00:00

abstract：:Alpha-1-antitrypsin detected by immunoperoxidase has been used as a marker for infiltrating monocytes on formalin-fixed, paraffin-embedded sections of 75 renal biopsies. Patients were classified on the basis of glomerular hypercellularity on light microscopy. Monocytes increased with increasing glomerular hypercellula...

journal_title：Clinical nephrology

authors： Laohapand T,Cattell V,Gabriel JR

更新日期：1983-06-01 00:00:00

abstract：:The clinical course and response to therapy of 16 patients with various complex forms of renovascular hypertension were investigated. Reconstructive surgery and/or transluminal dilatation was either ineffective (n = 5) or could not be performed for technical reasons (n = 11). The group contained 7 patients with multil...

journal_title：Clinical nephrology

authors： Lüscher T,Vetter H,Tenschert W,Greminger P,Pouliadis G,Kuhlmann U,Reutter F,Tuma J,Siegenthaler W,Vetter W

更新日期：1983-06-01 00:00:00

abstract：:We report the successful use of captopril for severe hypertension in three renal transplant recipients. Multiple drugs including minoxidil were ineffective in these patients. Bilateral nephrectomy also failed to control the hypertension in one patient. The addition of captopril resulted in excellent and sustained cont...

journal_title：Clinical nephrology

authors： Venkatachalam K,Kosanovich JM

更新日期：1983-05-01 00:00:00

abstract：:The effect of treatment with a protein-reduced diet (20-30 g/day) and essential amino acids was studied in 21 patients with diabetes mellitus and renal failure. The mean treatment time was 5.0 (0.5-14) months. Most patients experienced considerable amelioration of their uremic symptoms and the mean serum value was red...

journal_title：Clinical nephrology

authors： Attman PO,Bucht H,Larsson O,Uddebom G

更新日期：1983-05-01 00:00:00

abstract：:The accumulation and excretion of uremic middle molecules (MM) were assessed in 97 non-dialyzed azotemic patients with varying degrees of renal insufficiency. For comparison the excretion rates of MM were estimated in 12 normal subjects. By the use of combined gel filtration and ion exchange gradient elution chromatog...

journal_title：Clinical nephrology

authors： Asaba H

更新日期：1983-03-01 00:00:00

abstract：:Lung volumes, flows, flow volume loop, diffusing capacity and closing volume were studied in 7 patients (Group I) before, with 2 liter dialyzate in the peritoneal cavity and after 8 hours of peritoneal dialysis. The functional residual capacity, residual volume and the total lung capacity decreased (P less than 0.01, ...

journal_title：Clinical nephrology

authors： Ahluwalia M,Ishikawa S,Gellman M,Shah T,Sekar T,MacDonnell KF

更新日期：1982-11-01 00:00:00

abstract：:Plasma levels of the platelet markers betathromboglobulin and platelet factor 4 are elevated in patients with chronic renal failure, and their levels in hemodialysis patients increase further during exposure to the dialysis membrane. The effectiveness of a short acting inhibitor of platelet aggregation in reducing the...

journal_title：Clinical nephrology

authors： Buccianti G,Pogliani E,Miradoli R,Colombi MA,Valenti G,Lorenz M,Polli EE

更新日期：1982-10-01 00:00:00

abstract：:In 121 primary cadaver kidney grafts, a significant increase in graft survival has been observed in recipients transfused prior to transplantation, whatever the number of units received or the time of administration. This beneficial effect of blood transfusion was shown to be independent of the recipient's sex, blood ...

journal_title：Clinical nephrology

authors： Fradet Y,Roy R,Lachance JG,Noël R

更新日期：1982-08-01 00:00:00

abstract：:One hundred and fifty out of 944 European dialysis centers reported experience with patients suffering from psoriasis. Ninety-three centers returned special questionnaires on 97 patients with end stage renal failure (ESRF patients) and on 49 patients dialyzed for psoriasis but who had normal renal function (NRF patien...

journal_title：Clinical nephrology

authors： Kramer P,Brunner FP,Brynger H,Chantler C,Donckerwolcke RA,Jacobs C,Selwood NH,Wing AJ

更新日期：1982-08-01 00:00:00

abstract：:A total of 52 non-transplant and 16 transplant renal biopsies were examined for the presence of monocytes in the glomeruli using the non-specific esterase reaction. Four of the non-transplant and 4 of the transplant group were positive. The 4 non-transplant samples all showed the presence of granular IgG and C3 togeth...

journal_title：Clinical nephrology

authors： Harry T,Bryant D,Coles GA,Davies M,Fortt W

更新日期：1982-07-01 00:00:00

abstract：:A study of the clinical, etiological and histological features of the nephrotic syndrome occurring in 76 adults aged over 60 was performed. Membranous nephropathy was the most frequent type (40%). 32% of the cases of membranous nephropathy were associated with another disease which was a malignant one in 22% of the ca...

journal_title：Clinical nephrology

authors： Zech P,Colon S,Pointet P,Deteix P,Labeeuw M,Leitienne P

更新日期：1982-05-01 00:00:00

abstract：:In addition to a hemorrhagic diathesis, uremia is accompanied by a clotting tendency, caused by a marked fall in fibrinolytic capacity. Measurement of lysis time of whole blood diluted with phosphate and acetate buffers and of euglobulin lysis times showed that accumulation of inhibitors is primarily responsible. Thes...

journal_title：Clinical nephrology

authors： Canavese C,Stratta P,Pacitti A,Mangiarotti G,Racca M,Oneglio R,Vercellone A

更新日期：1982-02-01 00:00:00

abstract：:The nephrotoxicity of paracetamol (acetaminophen) administered to rats in doses of 300 mg/kg/day for periods up to 32 weeks was increased in the presence of experimentally induced pyelonephritis. The same dose of paracetamol failed to cause renal lesions in rats without pyelonephritis. Generally the pyelonephritic rea...

journal_title：Clinical nephrology

authors： Furman KI,Kündig H,Lewin JR

更新日期：1981-12-01 00:00:00

abstract：:The influence of antihypertensive therapy on plasma norepinephrine (NE) was examined in 58 patients with moderate chronic renal failure (CRF). Six normotensive patients not receiving antihypertensive medicines (mean serum creatinine 2.4 +/-.2 mg/dl) had a modest but significant increase in NE compared to normals in bo...

journal_title：Clinical nephrology

authors： Henrich WL,Mitchell H,Anderson S,Cronin R,Pettinger WA

更新日期：1981-09-01 00:00:00

abstract：:The effects of hemodialysis on cardiac rhythm and left ventricular function were evaluated by Holter electrocardiographic monitoring and M-mode echocardiography in 22 stable patients on regular hemodialysis in hospital. Significant ventricular arrhythmias occurred in 9%. Mean left ventricular volume in diastole (LVVd)...

journal_title：Clinical nephrology

authors： Macdonald IL,Uldall R,Buda AJ

更新日期：1981-06-01 00:00:00

abstract：:Two young men with anti-glomerular basement membrane (anti-GBM) antibody-induced Goodpasture's syndrome are described. Despite the characteristic renal morphological features and high titers of anti-GBM antibody, they had normal renal function. Both patients recovered spontaneously without treatment and remain well wi...

journal_title：Clinical nephrology

authors： Bailey RR,Simpson IJ,Lynn KL,Neale TJ,Doak PB,McGiven AR

更新日期：1981-04-01 00:00:00

abstract：:The excretion of N-acetyl-beta-glucosaminidase (Nag) was studied in 109 patients with glomerulonephritis. A positive correlation was found between the concentration of albumin and Nag in the urine. Almost all the urinary Nag had the properties of the tissues, not of the serum isoenzyme. The ratio between Nag and album...

journal_title：Clinical nephrology

authors： Hultberg B,Ravnskov U

更新日期：1981-01-01 00:00:00

abstract：:Serum Tamm-Horsfall glycoprotein (THG) concentrations were measured by radioimmunoassay in a group of 95 people with normal renal function and lay in the range of 70 to 540 ng/ml. None was detectable in 6 anephric patients. Patients on hemodialysis but with both kidneys in situ had concentrations below the lower limit...

journal_title：Clinical nephrology

authors： Dawnay AB,Cattell WR

更新日期：1981-01-01 00:00:00

abstract：:It has been suggested that antibodies to native DNA occur with some frequency in patients treated by hemodialysis. This has been attributed to the use of the technique. We have investigated 48 patients on maintenance dialysis for the presence of antibodies to single stranded DNA (ss-DNA) and native DNA (n-DNA) compare...

journal_title：Clinical nephrology

authors： Dasgupta MK,Davis P,Higgins MR,Dossetor JB

更新日期：1980-12-01 00:00:00

abstract：:We reviewed the clinical and renal biopsy information of 115 patients who presented with renal disease after the age of sixty years. The major clinical presentations were renal insufficiency in 57 patients, nephrotic syndrome in 35 patients, and hematuria with variable amounts of proteinuria in 23 patients. Crescentic...

journal_title：Clinical nephrology

authors： Moorthy AV,Zimmerman SW

更新日期：1980-11-01 00:00:00

abstract：:Intraplatelet and plasma serotonin levels were measured in 269 samples from 44 patients with systemic lupus erythematosus (SLE) and clinical nephritis. The intraplatelet serotonin levels were depressed and the plasma serotonin levels were raised in lupus nephritis. There was a strong correlation between both lowered i...

journal_title：Clinical nephrology

authors： Parbtani A,Frampton G,Yewdall V,Kasai N,Cameron JS

更新日期：1980-10-01 00:00:00

abstract：:The association of idopathic nephrotic syndrome (INS) with tubular dysfunction is uncommon. The authors report on 9 pediatric cases (6 girls and 3 boys). All the patients (age 12 to 48 months) presented initially with a pure INS. The syndrome was clinically severe and either initially or secondarily resistant to stero...

journal_title：Clinical nephrology

authors： Bouissou F,Barthe P,Pierragi MT

更新日期：1980-09-01 00:00:00

abstract：:The proposed role of parathyroid hormone as an important agent for the development of certain uremic complications could not be confirmed in studies correlating, in dialysis patients, the nerve conduction velocity and the serum lipids with four different immunochemically defined forms of circulating parathyroid hormon...

journal_title：Clinical nephrology

authors： Schaefer K,Offermann G,von Herrath D,Schröter R,Stölzel R,Arntz HR

更新日期：1980-08-01 00:00:00

abstract：:Vesicoureteric reflux (VUR) into transplanted kidneys has been cited as an often disregarded but frequent complication of transplantation which is associated with a glomerular lesion that resembles membranoproliferative glomerulonephritis, marked proteinuria, and graft failure. To determine the prevalence of this comp...

journal_title：Clinical nephrology

authors： McMorrow RG,Curtis JJ,Lucas BA,Williams C,McRoberts JW,Luke RG

更新日期：1980-08-01 00:00:00

abstract：:The fate of the contracted kidney in long-term hemodialysis patients was examined. Total kidney volume was measured by computer assisted tomography in 96 chronically hemodialyzed patients with chronic renal failure due to chronic glomerulonephritis. The presence of cysts and/or tumor in the renal parenchyma was evalua...

journal_title：Clinical nephrology

authors： Ishikawa I,Saito Y,Onouchi Z,Kitada H,Suzuki S,Kurihara S,Yuri T,Shinoda A

更新日期：1980-07-01 00:00:00

abstract：:IgA nephropathy, a condition thought to cause slowly progressive renal damage, is frequently associated with high serum IgA levels. As phenytoin sodium lowers serum IgA concentrations, a controlled trial of therapy with this drug was conducted over a two-year period in patients with IgA nephropathy. Despite significan...

journal_title：Clinical nephrology

authors： Clarkson AR,Seymour AE,Woodroffe AJ,McKenzie PE,Chan YL,Wootton AM

更新日期：1980-05-01 00:00:00